International Journal of Obesity - Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD Skip to main content Thank you ...

Fatty Acid Metabolism Disruption: In NAFLD, abnormal fatty acid metabolism in the liver contributes to lipid dysregulation, leading to an increase in circulating free fatty acids.

Non-alcoholic fatty liver disease (NAFLD), characterized by excessive hepatic lipid accumulation, poses a high prevalence and can progress to cirrhosis and liver cancer. To enhance preventive and ...

Further analysis showed that Asah1 deficiency increased harmful lipids accumulation, disrupted lipid metabolism, triggered cellular stress, and impaired the cell's waste disposal system.

image: A new Chinese Medical Journal review assesses the role of bile acids and lipid metabolism dysregulation in the progression of non-alcoholic fatty liver disease. view more Credit: Prof ...

Understanding more about how lipid metabolism is deregulated in cancer has not been as heavily researched. The researchers' future work focuses on understanding how BNIP3 is regulated in disease ...

The gene Asah1 plays a crucial role in preventing the progression of nonalcoholic fatty liver diseases (NAFLD) to more severe forms by regulating lipid homeostasis and cellular maintenance.

Understanding the link between Non-Alcoholic Fatty Liver Disease (NAFLD) and cardiovascular disease is essential. ... The liver plays a central role in lipid and cholesterol metabolism.