Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood ...

A hepatocellular carcinoma risk score using routine clinical data outdid the FIB-4 alone in identifying at-risk patients without viral hepatitis or cirrhosis.

Most children with CF treated at a San Francisco CF clinic did not receive CF liver disease screening in accordance with current guidelines.

Panelists discuss how emerging, better-tolerated oral therapies for idiopathic pulmonary fibrosis (IPF) and progressive ...

By establishing an iron overload-induced hepatic ferroptosis model, scientists from Japan have identified iFerroptosis—an ...

Chronic kidney disease (CKD) is typically associated with severe fibrosis, the exact pathogenesis of which remains unclear.

Introduction Idiopathic pulmonary fibrosis (IPF) is characterised by accumulation of fibroblasts and myofibroblasts and deposition of extracellular matrix proteins. Sphingosine-1-phosphate (S1P) ...

Liver fibrosis stages were evaluated semi-quantitatively according to the Metavir scoring-system [12] for patients infected with chronic hepatitis B or C. Liver fibrosis was staged on a F0-F4 ...

Alcohol-associated liver disease mortality doubled from 1999 to 2022, with pronounced increases among women, younger adults, and American Indian and Alaska Native populations, according to study ...

IBI3030 significantly reduces LDL-c (p<0.01 vs. baseline) and Lp(a), improves oral glucose tolerance (OGTT) (effective even in GLP-1R knockout mice), reduces body weight, and preserves insulin ...

Madrigal Receives Positive CHMP Opinion for Resmetirom (Rezdiffra™) for the Treatment of MASH with Moderate to Advanced Liver Fibrosis Provided by GlobeNewswire Jun 20, 2025, 3:30:32 AM ...

NEEDHAM, Mass., June 20, 2025 /PRNewswire/ -- Perceptive Discovery, a global leader in molecular and functional imaging research, today announced the launch of the FIBRE (Fibrosis Imaging ...