A hepatocellular carcinoma risk score using routine clinical data outdid the FIB-4 alone in identifying at-risk patients without viral hepatitis or cirrhosis.

Most children with CF treated at a San Francisco CF clinic did not receive CF liver disease screening in accordance with current guidelines.

Chronic kidney disease (CKD) is typically associated with severe fibrosis, the exact pathogenesis of which remains unclear.

IBI3030 significantly reduces LDL-c (p<0.01 vs. baseline) and Lp(a), improves oral glucose tolerance (OGTT) (effective even in GLP-1R knockout mice), reduces body weight, and preserves insulin ...

Liver fibrosis and necroinflammatory activity were semiquantitatively evaluated by the METAVIR scoring system. 22,23 Fibrosis (F) was staged on a four-point scale according to METAVIR (F0, no fibrosis ...

The cut-off values for liver fibrosis using MRE in the current study were 1.94, 2.90 and 3.6 kPa for fibrosis stage F1 (mild fibrosis), F2 (significant fibrosis) and ≥F3 (advanced fibrosis), ...

Looking at combined benefits, a third of patients taking semaglutide were able to see both resolution of steatohepatitis and reduction of liver fibrosis (32.7%), compared with 16.1% of patients ...

The diagnostic criteria to establish the presence of significant CLD was a liver biopsy indicating fibrosis stage ≥F1. If no biopsy was conducted, a person had to have radiological signs of CLD ...

Roche is rolling out a new diagnostic test to help assess hidden liver fibrosis in patients showing signs of metabolic dysfunction-associated steatotic liver disease, or MASLD. The company said ...

Reduction in liver fibrosis was observed among 36.8% of those receiving semaglutide compared with 22.4% of those receiving placebo (estimated difference, 14.4 percentage points; 95% CI, 7.5-21.3 ...

Liver fibrosis is sometimes reversible, especially when found and treated early. The goal of treatment is to stop or slow fibrosis progression, manage symptoms, and address or prevent complications.

The patients had a median fibrosis stage of 1, as determined by trichrome stain. A median stiffness of 8.2 kPa and a FIB-4 of 2.032 were both predictors of stage 2 fibrosis.