When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

A new study shows type I interferon fine-tunes macrophage mitochondria through the protein ISG15, boosting dead-cell ...

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an ...

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an ...

Researchers have identified an enzyme that controls the maturation and long-term survival of tissue-resident macrophages.

A microglia replacement approach demonstrates that brain macrophages with patient mutations from Aicardi–Goutières syndrome, a genetic, brain predominant interferonopathy, are sufficient to drive ...

Acute-on-chronic liver failure (ACLF) is a life-threatening syndrome characterized by systemic inflammation and immune dysregulation, in which ...

Ryan Allen, an assistant professor of physiology and cell biology at UAMS, will share a current project from his lab dedicated to developing a drug-responsive mouse model of atherosclerosis, a disease ...

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer ...

​A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer ...

Multiple sclerosis (MS) is a chronic neurological disease characterized by nerve damage and consequent impairments in vision, movement, balance and mental function. In MS, the immune system mistakenly ...