With the rising epidemic of obesity, metabolic syndrome ... spectrum of diseases ranging from simple fatty liver to non-alcoholic steatohepatitis (NASH) and can progress to fibrosis, cirrhosis ...

The liver is essential for digestion, metabolism, detoxification, and fluid regulation. While alcohol abuse is a known cause ...

A European Medicines Agency committee, on Thursday, accepted the use of an artificial intelligence (AI) tool called AIM-NASH ...

Non-alcoholic fatty liver disease (NAFLD) represents the most common liver disease worldwide affecting approximatively 20–30% ...

However, today's lifestyle of poor diet choices and lack of exercise can cause too much fat to build up in the liver, leading to a range of metabolic conditions like NAFLD. It is estimated that ...

NAFLD can remain harmless, but in some patients it progresses to non-alcoholic steatohepatitis (NASH). Metabolic dysfunction-associated steatotic liver disease (MASLD) is a heterogeneous disease ...

However, if liver fat continues to accumulate, it can lead to non-alcoholic steatohepatitis (NASH), a more ... Additionally, fatty liver disease is closely linked to metabolic disorders such ...

Investigators have found that the gene Asah1 plays a crucial protective role in preventing the progression of nonalcoholic fatty liver diseases (NAFLD) into more severe forms of liver disease by ...

Non-Alcoholic Fatty Liver Disease (NAFLD) is emerging as a significant global health concern, driven by increasing rates of obesity, diabetes and sedentary lifestyles. NAFLD includes a spectrum of ...

has long been recognized as a key mechanism responsible for liver damage and disease progression in NAFLD. [18] Enhanced oxidative stress occurs in the liver of patients with NASH, as well as in ...