Liver fibrosis is a major global health concern, developing as a result of chronic liver diseases (CLDs) such as viral ...

High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in mice.

A novel strategy using lipid nanoparticles to reprogram liver immunity shows promise in generating antitumor responses ...

A research team led by Prof. SUN Cheng from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, along with ...

The gene expression data and immune cell infiltration information derived from TCGA database ... First, 1x10 6 cells were injected into the liver of each mouse with an injection volume of 40 µL.

Published today (March 7) in Science Advances, the study is the first to show that ammonia buildup, known as hyperammonaemia, directly harms liver cells. It also details how this damage occurs in ...

Liver diseases ... attracting effector T cells to the TME and ultimately enhancing the destruction of tumor cells. This culminates in the conversion of a “cold” tumor microenvironment, characterized ...