Weight loss is a key effect of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), but these drugs may also provide liver ...

The tool reduces pathologist variability in liver biopsy assessment during trials of treatments for metabolic ...

PathAI, a global leader in AI-powered pathology, today announced that the European Medicines Agency (EMA) Committee for ...

The liver is the body’s chemical factory, where most metabolic processes take place. It processes everything you eat and drink, converting them into energy and essential nutrients. Additionally, the ...

While Kevin Nash is a controversial figure due to backstage politics in WWE and WCW, Big Daddy Cool formed strong friendships over the years. His best work might actually be in Channing Tatum's Magic ...

Discover preclinical studies that indicate that empagliflozin reduces liver fat, improves liver function markers, and decreases inflammation.

While researchers didn’t notice changes in the gut microbiome overall after a three-day juice-only diet, they found an increase of specific unhealthy bacteria linked to inflammation and ...

Finally, we determined the influence of hepatocyte-specific PPARα deficiency in different models of steatosis and during ageing. Peroxisome proliferator-activated receptor α (PPARα) is a nuclear ...

Inflammation – your immune system’s response to injury or infection – can be a good thing. When there is inflammation in the body for a short time, in response to a harmful stimulus, it can ...

(30) discovered that hepatokine ORM2 directly binds to membrane IP3R2 through autocrine/paracrine mechanisms, subsequently activating the CaMKK2-AMPK pathway to regulate lipid metabolism and improve ...

While reduction of hepatic steatosis may not be the most desirable ... is essential for the histological diagnosis of adult NASH. Portal inflammation is increasingly recognized as an important ...

Meanwhile, resmetirom, a selective THR-β agonist, has received FDA breakthrough therapy designation due to its ability to reduce hepatic steatosis and inflammation. Additionally, dual PPARα/γ ...