Weight loss is a key effect of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), but these drugs may also provide liver ...

The tool reduces pathologist variability in liver biopsy assessment during trials of treatments for metabolic ...

PathAI, a global leader in AI-powered pathology, today announced that the European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP) has granted full qualification for ...

Discover preclinical studies that indicate that empagliflozin reduces liver fat, improves liver function markers, and decreases inflammation.

This complex liver disorder ranges from simple steatosis to more severe ... key processes such as lipid metabolism, inflammation, apoptosis, and fibrosis in MAFLD. Several transcription factors ...

The MAFLD spectrum and treatment options for MAFL and MASH. Transcriptional regulation of steatosis, inflammation, apoptosis, and fibrosis in the progression of MAFLD. SHANNON, CLARE, IRELAND ...

Non-Alcoholic Fatty Liver Disease (NAFLD) is emerging as a significant global health concern, driven by increasing rates of obesity, diabetes and sedentary lifestyles. NAFLD includes a spectrum of ...

However, steatosis can progress ... viruses can cause liver fibrosis without the preceding fatty liver stages. Medications such as non-steroidal anti-inflammatory drugs, anabolic steroids, birth ...

The team revealed distinct phases where waves of immune responses give way to lung fibrosis—scarring of ... of cellular mechanisms underlying inflammatory responses in severe disease.

About 25% of NAFLD patients progress to a more severe stage including liver inflammation (nonalcoholic steatohepatitis, NASH) and scarring (liver fibrosis), which can lead to cirrhosis or even liver ...

About 25% of NAFLD patients progress to a more severe stage including liver inflammation (nonalcoholic steatohepatitis, NASH) and scarring (liver fibrosis), which can lead to cirrhosis or even ...

Hepatic fat accumulation can progress from simple NAFLD to non-alcoholic steatohepatitis (NASH) which includes hepatocellular injury, inflammation, and fibrosis. In more severe cases ...