Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

Fibrosis scores did not change, but zone 3 perisinusoidal fibrosis changed from a qualitative assessment of dense to delicate in 33% of cases.

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

The COVID-19 pandemic engulfed the U.S. five years ago this month, leaving not only lingering mental health effects but also long-term physical symptoms. One of those included a condition known as ...

Get Instant Summarized Text (Gist) Approximately 10% of South Asian immigrants aged 45 and older in Canada have hypothyroidism, with a 77% higher likelihood compared to Canadian-born individuals ...

Cystic fibrosis (CF) treatment typically involves procedures and medications that help clear the airways. Other treatments may include antibiotics, pancreatic enzymes, a high-calorie diet, and ...

Fibrosis is the formation of fibrous connective tissue in response to injury. It is characterized by the accumulation of extracellular matrix components, particularly collagen, at the site of injury.

1 Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Department of Basic Medicine, Gannan Medical University, Ganzhou, China 2 Department ...

Background Intestinal fibrosis resulting in stricture formation and obstruction in Crohn’s disease (CD) and increased wall stiffness leading to symptoms in ulcerative colitis (UC) is among the largest ...

EaStCHEM School of Chemistry, University of Edinburgh, David Brewster Road, Edinburgh, Scotland EH9 3FJ, U.K.