Researchers in Göttingen, Germany, have elucidated the structure and function of otoferlin, a protein that plays a crucial ...

Scientists at the Ruđer Bošković Institute (RBI) in Zagreb, Croatia, have discovered that the protein CENP-E, long believed ...

Motor proteins are tiny "machines" inside cells that use chemical energy to move along molecular tracks and carry out essential processes like chromosome segregation during cell division. When a cell ...

ESMs, a proteome-scale framework to classify loss-of-function missense variants into distinct mechanistic groups by combining two complementary state-of-the-art machine learning models. The strength ...

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can ...

The first full-length structures of two heat shock chaperone proteins in a complex reveal the key structural region regulating their function, according to a new study from St. Jude Children's ...