Acute-on-chronic liver failure (ACLF) is a life-threatening syndrome characterized by systemic inflammation and immune dysregulation, in which ...
SPP1+ macrophages identified as key drivers and therapeutic targets in colorectal cancer progression
(A) Volcano plot of DEGs in monocytes/macrophages between NC and CRC samples in the GSE164552 dataset. (B) Venn diagrams of common DEGs up- or down-regulated across the six scRNA-seq datasets (NC vs.
Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium urate crystals, or MSUc; CPPD disease, another inflammatory joint disease ...
Macrophages are the specialized phagocytic cells that respond to toxic particle depositions to exert inflammatory and clearance responses. These long-lived immune cells engulf foreign substances like ...
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