Roche's Genentech unit has started work on a $700 million manufacturing facility in North Carolina, part of a promised $50 billion investment in the US. The plant – its first on the East Coast of the ...

Roche has staked a claim to use its oral selective oestrogen receptor degrader (SERD) giredestrant as a second-line therapy for breast cancer, regardless of a patient's ESR1 mutation status. Top-line ...

Binding buffer: 5 mM Tris-HCl (pH 7.5), 0.5 mM EDTA, 1 M NaCl Breaking buffer: 10 mM Tris-HCl (pH 7.5), 1% Triton-X 100, 1% SDS, 100 mM NaCl, 1 mM EDTA Primers 1 and 2 are used for preamplification of ...

Using the procedure reported here, all the pipetting steps in LM-PCR can be performed on a Biomek 2000 liquid handling robotic workstation. After thermocycling is completed in the first reaction, the ...