Scientists uncover how TBK1 and IKKε prevent premature cell death and inflammation
New research from the Kennedy Institute has revealed how two important proteins, TBK1 and IKKε, play a crucial role in ...
EMBO Press18h
HDAC6 deacetylates ENKD1 to regulate mitotic spindle behavior and corneal epithelial homeostasis
HDAC6 is upregulated in corneal diseases and causes ENKD1 deacetylation at lysine 98. Deacetylation of ENKD1 blocks its ...
Women's Health15d
Juice Cleanses Might Cause Inflammation And Disrupt Gut Health, According To A New Study
While researchers didn’t notice changes in the gut microbiome overall after a three-day juice-only diet, they found an increase of specific unhealthy bacteria linked to inflammation and ...
i17d
10 foods that can reduce inflammation - and how to cook them to boost the benefits
Inflammation – your immune system’s response to injury or infection – can be a good thing. When there is inflammation in the body for a short time, in response to a harmful stimulus, it can ...
The Lancet18d
The intestinal barrier: a pivotal role in health, inflammation, and cancer
The subsequent activation of the immune system has an important role in the pathogenesis of inflammatory bowel disease, as well as in metabolic dysfunction-associated steatohepatitis, primary ...
ahajournals.org18d
Albuminuria in Cardiovascular, Kidney, and Metabolic Disorders: A State-of-the-Art Review
Department of Medicine, Boston Medical Center, MA (S.E.C., A.V.). Department of Medicine, Section of Nephrology, Boston University Chobanian & Avedisian School of ...
Business Wire18d
Ventus Therapeutics Announces First Patient Dosed in Phase 2a Clinical Trial Evaluating VENT-02, an Oral, Brain-Penetrant NLRP3 Inhibitor, in Parkinson’s Disease
an inflammatory form of cell death. Therapeutic inhibition of NLRP3 can prevent the formation of the NLRP3 inflammasome, which in turn inhibits the production of IL-1β and IL-18 as well as ...
Medical News Today23d
What to know about inflammatory bowel disease
Inflammatory bowel disease (IBD) refers to long-term conditions that involve inflammation of the digestive tract or gut. It can lead to a range of digestive symptoms. According to the Centers for ...
BMJ25d
Neutrophil microvesicles resolve gout by inhibiting C5a-mediated priming of the inflammasome
Objectives Gout is a highly inflammatory but self-limiting joint disease induced by the precipitation of monosodium urate (MSU) crystals. While it is well established that inflammasome activation by ...
CBSSports.com26d
Flau'Jae Johnson injury: LSU's leading scorer shut down through SEC Tournament due to shin inflammation
No. 7 LSU's leading scorer Flau'Jae Johnson will miss the SEC Tournament due to shin inflammation, coach Kim Mulkey revealed during the pregame radio show ahead of the Tigers' 85-77 loss to Ole ...