The growth rate of the atmospheric abundance of methane (CH 4) reached a record high of 15.4 ppb yr −1 between 2020 and 2022, but the mechanisms driving the accelerated CH 4 growth have so far been ...

In the secretory pathway, the pH within organelles is gradually acidified, starting at 7.1 to 7.2 in the endoplasmic reticulum, decreasing to 6.0 to 6.7 in the Golgi apparatus/trans-Golgi network ...

Sorting cells with target metabolic functions from a mutant pool exhibiting substantial genetic diversity is often the rate-limiting step in synthetic biology. Here, we developed a label-free, ...

The synthesis of new polyhydrides with high superconducting Tc is challenging owing to the high pressures and temperatures required. In this study, we used machine-learning potential molecular ...

Natural ice plays salient roles in making the Earth habitable and sustainable. Previously overlooked, its role in chemical processes is now of emerging interest, particularly due to the freeze ...

The prostaglandin D2 receptor (DP1) functions as a critical regulator of diverse physiological processes, including sleep–wake cycles, allergic responses, and inflammatory cascades. By determining ...

Greening immediately after etiolated-seedling’s emergence from the soil is critical for plants to initiate their autotrophic life cycle through photosynthesis. The greening process relies on a complex ...

Self-reproduction is one of the most fundamental features of natural life. This study introduces a biochemistry-free method for creating self-reproducing polymeric vesicles. In this process, ...

Calcineurin is a highly conserved phosphatase that plays a central role in sensing calcium and governing transcriptional, posttranscriptional, and posttranslational signaling networks. Calcineurin is ...

As AI tools become increasingly prevalent in workplaces, understanding the social dynamics of AI adoption is crucial. Through four experiments with over 4,400 participants, we reveal a social penalty ...

Final body size at developmental maturity often correlates with maximum lifespan (10 – 13). For instance, smaller individuals within a species often live longer than larger ones (11). In contrast, the ...

The proteasome is a protein complex that degrades proteins by cleaving substrates into smaller peptides. Most unwanted cellular proteins are earmarked for proteasome-mediated degradation by multimers ...