Hypophosphatasia is a relatively common skeletal disease that primarily affects bone and tooth strength. In the third ...

Hypophosphatasia is a relatively common skeletal disease that primarily affects bone and tooth strength. In the third national dental survey of hypophosphatasia in Japan, recently published in ...

SINCE Gomori 1 and Takamatsu 2 adopted a histochemical test for the demonstration of alkaline phosphatase, many investigators have examined the distribution of the enzyme in animal tissues ; the ...

Artificial intelligence (AI) models have been used to study the compositional regularities of proteins in nature, enabling it to assist in protein design to improve the efficiency of protein ...

which is remakably more stable than the wild type in the alkaline environment of industrial production. Figure 4C shows the variation in yield during affinity chromatography across multiple cycles ...

Alkaline phosphatase is an enzyme. An enzyme is a type of protein that catalyzes (causes or accelerates) chemical reactions in the body. ALP is produced mainly by the liver and bones but is also ...

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.biomac.4c01484. Reaction scheme for the solid-phase peptide synthesis ...

Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia ...

Nature Research Intelligence Topics enable transformational understanding and discovery in research by categorising any document into meaningful, accessible topics. Read this blog to understand ...