LANGHORNE, PA — PANTHERx Rare Pharmacy and Savara Inc. (Nasdaq: SVRA) announced an exclusive U.S. distribution agreement for MOLBREEVI, an investigational inhaled therapy under FDA review for a rare ...

Though the COVID-19 pandemic provided a brief respite, influenza virus is back in circulation and, as usual, poses a special danger to people over the age of 65. But why are older people more ...

Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal conditions, these cells act as guardians, keeping the lungs healthy, supporting breathing, and ...

Autoimmune pulmonary alveolar proteinosis (aPAP) is a rare disease characterized by progressive surfactant accumulation and hypoxemia caused by autoantibodies against granulocyte–macrophage ...

Version of Record: This is the final version of the article. The concept that trained immunity, as defined, can be beneficial to subsequent immune challenges is important in the broad context of ...

Lung macrophages, a type of white blood cell vital for immune defense, play a crucial role in conditions such as idiopathic pulmonary fibrosis (IPF). There are two main varieties of these cells in the ...

Recently these monocyte-derived alveolar macrophages, or Mo-AMs, were identified as key drivers of lung fibrosis disease progression. However, the mechanisms of their pro-fibrotic behavior and ...

BIRMINGHAM, Ala. – Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages — the white blood cells that defend the body by killing microbes, ...

The concept of trained immunity has transformed our understanding of how the innate immune system responds to stimuli. For many years, the responses of innate immune cells – such as monocytes, ...

Introduction: Idiopathic pulmonary fibrosis is a progressive lung disease with a poor prognosis. Alveolar macrophages (AMs) are essential for maintaining lung homeostasis and play a significant role ...