The farnesoid X receptor (FXR) is a bile acid ... and side chain structure, they identified DC646 as the most potent FXR antagonist, with an inhibition rate exceeding 70%. Molecular docking ...

Long before laboratories and clinical trials, indigenous healers recognized the extraordinary properties of miracle leaf.

BA synthesis is governed by host homeostasis, and compositional alterations of BAs inversely reshaped the gut microbiota structure ... bile acids. How supplemented BAs benefit or hamper the ...

Natsagdorj, D. , Altangerel, A. , Munkhjargal, N. and Tuul, K. (2025) A Core Concept of Health in Mongolian Traditional ...

More information: Antoine Jalil et al, Bile acid 7α-dehydroxylating bacteria accelerate injury-induced mucosal healing in the colon, EMBO Molecular Medicine (2025). DOI: 10.1038/s44321-025-00202-w ...

A research team has made further progress in the treatment of intestinal inflammation. A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of ...

A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of pro-inflammatory T helper 17 cells (TH17) and at the same time promotes the generation of ...

Linoleic acid, an omega-6 fatty acid found in seed oils such as soybean and safflower oil, and animal products including pork and eggs, specifically enhances the growth of the hard-to-treat 'triple ...

Zeolites and zeotypes are widely used in the energy and chemical industries due to their unique pore structures and excellent ...

Iowa State University researchers evaluated imidazolium-based ZILs with sulfonate and triflimide anions to understand the ...

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, but ...