[6] Initiation refers to early paracrine-mediated changes in gene expression and phenotype that render the cells responsive to other cytokines ... Kupffer cells, hepatocytes, platelets, and ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

Atherosclerosis (AS) is a chronic inflammatory disease characterized by the buildup of lipids and immune cells in arterial ...

Figure 1: a, Schedule of DMN administrations and HGF–HVJ liposome or PBS injections. Figure 3: a–c, Liver sections of rats after DMN administration. Sprague–Dawley rats 4–5 weeks old and ...

Results showed the agent lessened severity of cytokine release syndrome or immune effector cell-associated neurotoxicity syndrome (ICANS) for a majority of treated patients. “We expected to see ...

Hepatocellular DILI is linked to inflammation, apoptosis, and necrosis ... which can lead to hepatocyte and cholangiocyte damage. UDCA mitigates these effects by replacing toxic bile acids ...

Hepatocellular DILI is characterized by inflammation, necrosis, and apoptosis, while cholestatic ... and immune-mediated ...

Marburg virus belongs to the genus Marburgvirus in the family Filoviridae and causes a severe hemorrhagic fever, known as Marburg hemorrhagic fever (MHF), in both humans and nonhuman primates ...

MicroRNAs (miRNAs) are key contributors to liver diseases progression. This study investigated hepatocyte-abundant miRNAs dysregulated by ALD, its impact on hepatocyte injury and the underlying basis.

In this review, we cover recent discoveries in new targets and molecules for antifibrotic treatment, which target pathways intertwined with the fibrogenesis process, including lipid metabolism, ...

Hypoxia has been postulated to be among the factors determining the differentiation of MSCs, resulting in the production of inflammatory cytokines throughout the process of tissue regeneration and ...