When you strain your back or burn your arm, receptor cells send messages along your nerve pathways to your brain. This results in a feeling of pain, a signal from your body that you must tend to it; ...

When living with chronic pain, over time, the brain becomes hypersensitive to pain signals, which increases pain. Pain is a danger signal. When something happens, such as touching a hot surface or ...

A widely prescribed opioid painkiller showed limited effectiveness and increased risk of negative effects in a new analysis published in BMJ Evidence-Based Medicine. The study examined tramadol, a ...

Chronic pain might quietly push people toward developing high blood pressure—and the more widespread the pain, the greater the danger. A massive analysis of over 200,000 adults uncovered strong links ...

Artificial intelligence is helping health-care providers better assess their patients’ discomfort. For years at Orchard Care Homes, a 23‑facility dementia-care chain in northern England, Cheryl Baird ...

Tramadol, a potent synthetic opioid, has been widely used to treat moderate to severe pain, but a new study suggests that the medication’s potential risks outweigh its “limited” benefits for chronic ...

It is a common misconception that because women are able to give birth and routinely deal with sometimes agonizing period cramps, they are somehow better able to tolerate pain than men. (It is ...

EDITOR’S NOTE: Chief Medical Correspondent Dr. Sanjay Gupta’s new book, “It Doesn’t Have to Hurt,” is available now. Watch “Dr. Sanjay Gupta Reports: It Doesn’t Have to Hurt.” at 9 p.m. ET on ...

Ed Mowery, the founder and lead singer of a death metal band, suffered unfathomable pain for decades: "It was 24/7, 365," he said, likening it to "lightning bolt razor snakes in my legs and nerve pain ...

A guitarist in a death metal band was one of several people who found that personalized deep brain stimulation eased their pain and helped them reduce pain medication. A guitarist in a death metal ...

Almost everyone has pain sometimes. It might start as a twinge in your back, a dull ache in your knee, a tingling on the bottoms of your feet. Maybe you slept funny, or hoisted a full bag of groceries ...

Knee pain is a common problem among adults of all ages. It can have many causes, including arthritis, traumatic injury, and stress on structures of the knee over time. Sometimes knee pain is mild and ...