Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

Instead, CICR acts as a dormant but dangerous silent risk factor, staying quiet under normal conditions yet becoming a major driver of pathology when RyR1 signaling is disrupted. This model resolves a ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Seattle Mariners right-hander Bryan Woo has been diagnosed with minor inflammation in his pectoral muscle, according to what manager Dan Wilson told reporters ahead of Saturday's game versus the ...

OTTAWA, July 31 (Reuters) - Canada's Gross Domestic Product shrank 0.1% in May on a monthly basis as expected but is likely to regain the lost ground in June as some sectors rebound, data showed on ...

School of Mechanical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China Shandong Institute of Mechanical Design and Research, Jinan 250353, China School of ...

Patients undergoing cardiac surgery often receive red-cell transfusions, along with the associated risks and costs. Early intraoperative normovolemic hemodilution (i.e., acute normovolemic ...

Abstract: The study aimed to investigate changes in corticomuscular coupling during elbow flexion and extension in stroke survivors using functional near-infrared spectroscopy (fNIRS) and surface ...

Abstract: Cardiomyocytes (CMs) are the contractile motors of the heart that generate the force required to pump blood into the systemic circulations. Its contractive process can be described as ...

USDA’s January Cattle Inventory report shed some much-needed light on the state of the cattle industry in the United States. USDA’s National Agricultural Statistics Service (NASS) previously published ...