The former Vikings, Raiders and Patriots star disclosed that he underwent a six-hour operation on his pancreas, liver, gall bladder and bile duct — commonly known as a Whipple procedure.

Free (unconjugated) bile acids were consistently demonstrated in ileal samples, and occasionally in lower jejunal samples, by thin-layer chromatography, supplemented in some cases by gas/liquid ...

In liver fibrosis cases, both the gut microbiota and bile acid metabolism are disrupted. As metabolites of the gut microbiota, bile acids have been linked to the progression of liver fibrosis via ...

A recent study in an animal model provides direct evidence for the role of the vagus nerve in gut microbiome-brain ...

Ursodeoxycholic acid (UDCA) is a bile acid (BA) approved by the U.S. Food and Drug Administration for the treatment of primary biliary cholangitis. It is also the major active component of bear bile ...

FGF19 negatively regulates bile acid synthesis and recombinant FGF19 increases the metabolic rate of mice. Unfortunately, FGF19 transgenic mice develop hepatocellular carcinomas, and this side ...

Salk Institute researchers found that regulating bile acids—specifically reducing harmful ones and increasing UDCA—can enhance T cell function and potentially make immunotherapy more effective for ...

Fatty acids are organic acids with at least one carboxyl (-C(=O)OH, -COOH or -CO2H) group and a long carbon chain that can be joined by double bonds, as in unsaturated fatty acids, or single bonds ...

Red yeast rice has been used as an alternative to statins in statin-intolerant patients. The bile acid sequestrants can reduce LDL-C by 10–20% when used as monotherapy. The addition of niacin to ...

We review the microbial metabolites that contribute to the development of NAFLD, such as trimethylamine, bile acids, short-chain fatty acids and ethanol. We discuss the mechanisms by which metabolites ...

All procedures carried out in this experiment were reviewed and approved by the Animal Protocol Review Committee of the University of Agriculture, Faisalabad. The experiment was conducted at the ...

Gallstone disease is the most common disorder affecting the biliary system, the body's system of transporting bile. Gallstones are solid, pebble-like masses that form in the gallbladder or the biliary ...