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Results of an autopsy-based study revealed that sudden cardiac death and multiorgan pathology may be more closely linked to SSc than previously thought.
Fibrosis staging may also be based on other tests outside of a liver biopsy and histology. For example, a doctor may confirm liver fibrosis with a blood test that measures fibrosis 4 (Fib4) in the ...
FibroMAP combines the power of high-resolution, single-fiber, and spatially resolved datasets generated by PharmaNest's digital pathology and image analysis platform (FibroNest) with advanced ...
Histological improvement in fibrosis (≥1 stage) was demonstrated in 39% of subjects according to NASH CRN, in 61% of subjects by ranked assessment with a highly statistically significant (p<0. ...
Histology findings from paired liver biopsies showed strong improvement in fibrosis without worsening of NASH, consistent with dose-dependent reduction of all biomarkers related to fibrogenesis ...
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News Medical on MSNExploring the dual role of microRNA-223 in hepatic fibrosisAnnouncing a new article publication for BIO Integration journal. Liver fibrosis is caused by excessive extracellular matrix ...
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Study identifies novel pathway with potential to slow the progression of pulmonary fibrosisMore information: Margaret A.T. Freeberg et al, Piezo2 Is a Key Mechanoreceptor in Lung Fibrosis that Drives Myofibroblast Differentiation, The American Journal of Pathology (2025). DOI: 10.1016/j ...
Data derived from: Loomba R, et al. Denifanstat, a fatty acid synthase (FASN) inhibitor, shows significant fibrosis improvement and MASH resolution in FASCINATE-2, a phase 2b 52-week international ...
This builds on previous findings of a phase 2 trial where 59% of patients taking semaglutide saw this outcome compared with 17% taking placebo (P < .001). 3 Meanwhile, reduced liver fibrosis ...
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