EMBO Press1d
Liver TET1 promotes metabolic dysfunction-associated steatotic liver disease
Liver TET1 was found to promote metabolic dysfunction-associated steatotic liver disease (MASLD) by regulating CD36 ...
eLife9d
Identification and comparison of orthologous cell types from primate embryoid bodies shows limits of marker gene transferability
The authors have generated important resources such as a reference dataset of early primate development by utilizing single-cell transcriptomic technology together with induced pluripotent stem cells ...
IEEE9d
Pathological Section Staining Transferring with Tailored Metric-based Model Selection
Abstract: As the important pathological section staining, Immunohistochemistry (IHC) staining uses labeled antibodies to highlight specific antigens, providing clearer results for malignancy ...
gut.bmj21d
Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD
Objective Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor expressed in tissues with high oxidative activity that plays a central role in metabolism. In this work, we ...
gut.bmj20d
miRNA-132 induces hepatic steatosis and hyperlipidaemia by synergistic multitarget suppression
1 The Silberman Institute of Life Sciences and the Edmond and Lily Safra Center for Brain Science, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Jerusalem, Israel Objective Both ...
Frontiers10d
An integrative pharmacology-based study on the pharmacological activity and mechanism of xiaoji-chenpi formula (XCF) against MAFLD
Metabolic-associated fatty liver disease (MAFLD) is a common chronic metabolic disease worldwide that seriously threatens human health. The Xiaoji-chenpi formula (XCF), derived from QingGanSan (QGS), ...
Frontiers29d
Reversed role of CD36 deficiency in high-fat diet or methionine/choline-deficient diet-induced hepatic steatosis and steatohepatitis
Introduction: Cluster of differentiation 36 (CD36) is highly expressed in the liver of patients with metabolic dysfunction-associated fatty liver disease (MAFLD) or metabolic dysfunction-associated ...