One study showed small cell lung cancer (SCLC) tumors with higher DNA damage response (DDR) activity were initially more sensitive to chemotherapy but had worse overall survival.

New research has provided insight into the biological mechanisms that may contribute to poor outcomes in certain cases of ...

During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

Everest Medicines (HKEX 1952.HK, "Everest", or the "Company"), a biopharmaceutical company focused on the discovery, clinical development, manufacturing, and commercialization of innovative ...

A research team led by Mount Sinai has uncovered mechanisms of abnormal immune cell function that may lead to Crohn's disease ...

New research shows how a specially trained population of immune cells keeps the peace by preventing other immune cells from attacking their own. The study provides a better understanding of immune ...

Scientists have uncovered a critical piece of the puzzle in autoimmune diseases: a protein that helps release immune response ...

A research team led by Mount Sinai has uncovered mechanisms of abnormal immune cell function that may lead to Crohn's disease ...

Researchers suggest discoveries may lead to new strategies for treating skin diseases, inflammation, diabetes, and ...

Our blood consists of many cell types that develop through different stages from a precursor type—the blood stem cell. An ...

Scratching your skin can feel satisfying, but learn how it impacts inflammation and bacterial infection defense.