A crucial mechanism in immune response: NOTCH signaling pathway plays essential role in CD8⁺ T cell differentiation
Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque's team at the Montreal Clinical ...
EMBO Press1d
PARP7 as a new target for activating anti-tumor immunity in cancer
PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...
Mirage News11d
Chinese Scientists Create System to Predict Liver Cancer Return
A research team led by Prof. SUN Cheng from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, along with ...
AHA/ASA Journals12d
Myeloid Fatty Acid Metabolism Activates Neighboring Hematopoietic Stem Cells to Promote Heart Failure With Preserved Ejection Fraction
BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...
gut.bmj15d
Novel microenvironment-based classification of intrahepatic cholangiocarcinoma with therapeutic implications
Correspondence to Dr Daniela Sia, Division of Liver Diseases, Department of Medicine ... molecular iCCA classifier that incorporates elements of the stroma, tumour and immune microenvironment (‘STIM’ ...
Quercetin: A natural solution with the potential to combat liver fibrosis
Liver fibrosis is a major global health concern, developing as a result of chronic liver diseases (CLDs) such as viral ...
CBS News18d
What is measles immune amnesia? Doctor explains how the virus infects immune cells
"Measles infects immune cells, and when it does so, it damages immune cells and it partially wipes out your immune system's memory to certain infections, so that leaves you more susceptible to ...
SciTech Daily18d
The Hidden Toxin Destroying Liver Cells – And the Breakthrough That Might Save Them
which leads to mitochondrial damage and a dangerous form of cell death that not only harms the liver but also other organs, including the immune system. There was also increased activity in the TLR4 ...
Science Daily19d
Ammonia build-up kills liver cells but can be prevented using existing drug
which leads to mitochondrial damage and a dangerous form of cell death that not only harms the liver but also other organs, including the immune system. There was also increased activity in the ...
UCL19d
Ammonia build-up kills liver cells but can be prevented using existing drug
which leads to mitochondrial damage and a dangerous form of cell death that not only harms the liver but also other organs, including the immune system. There was also increased activity in the TLR4 ...
gut.bmj22d
Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage
acute liver failure chronic liver disease hepatic stellate cell inflammation immune-mediated liver damage This is an open access article distributed in accordance with the Creative Commons Attribution ...
Frontiers24d
PRR13 expression as a prognostic biomarker in breast cancer: correlations with immune infiltration and clinical outcomes
Additionally, we investigated the relationship between PRR13 mRNA expression and immune cell infiltration in breast cancer (BRCA) using two methodologies. Furthermore, a retrospective analysis of 160 ...