Irvine Co. is currently building 3,000 units at three sites in Orange County with plans for 9,000 more across California.

The University of California, Irvine has licensed a new cancer-fighting immunotherapy to biotech firm GlyTR Therapeutics Inc.

Super Irvine International Market returns to the city of Irvine this month at Parkview Center on University Drive.

A $2 million lawsuit claims city consultants drastically understated contamination at the Great Park and stalled on change ...

The campaign’s final weeks have turned into a statewide scramble to persuade California voters to temporarily override the ...

Video producer Nathan Gopen will talk about the history of Irvine at 7 p.m. on Oct. 21 with author Mike Stockstill at Sherman ...

THERE’S A LOT TO SEE AND LEARN HERE AT IRVINE NATURE CENTER, BUT THIS WEEK THEY’RE TRADING IN REAL SPIDERS FOR THESE GUYS FOR ...

UC Irvine has acquired the Orange County Museum of Art, including its building, staff, assets and debt; the Hammer's biennial 'Made in L.A.' opens; and Dua Lipa plays five nights at the Forum.

An Orange County businessman is speaking out about a possible mistake he made that likely made him the target of a violent ...

A man was killed Monday in a multi-vehicle crash on the Santa Ana (5) Freeway in Irvine. The crash was reported about 8:30 ...

Irvine City Council members voted against banning the sale of nitrous oxide, also known as whippets, for recreational drug use, while other Orange County cities crack down on the inhalant.