Researchers at University of Tsukuba have discovered that an immunosuppressive drug affects microglia, the resident immune ...

A key molecular mechanism drives the growth of liver cell cancer while simultaneously suppressing the body's immune response ...

Primary biliary cholangitis (PBC) is a rare chronic autoimmune cholangiopathy that mainly affects middle-aged women, ...

Metabolic dysfunction-associated steatohepatitis (MASH) and type 2 diabetes mellitus (T2DM) are closely linked conditions that share common disturbances in metabolism, inflammation, and fibrotic ...

Biliary atresia (BA) is a life-threatening liver disease of infancy in which early surgery can restore bile flow but rarely halts long-term liver injury.

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic tangles overwhelm normal repair pathways, cells flip on a fast but error-prone ...

Researchers have found a small but powerful switch inside breast cancer cells that helps them survive stressful conditions. When this switch flips, the cells activate protective programs that make ...

Immunotherapy has revolutionized the way physicians treat patients. Previously, chemotherapy was the standard-of-care with the goal to eliminate tumor cells by dysregulating their ability to ...

Immune cells rush in and signal nearby fat cells to break down, releasing natural fatty acids that "switch on" dormant hair-follicle stem cells and kick-start growth. The researchers used a topical ...

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children's Research Hospital scientists recently ...