Atherosclerosis (AS) is a chronic inflammatory disease characterized by the buildup of lipids and immune cells in arterial ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

Prof. Shan Tizhong's team at Zhejiang University discovered that lard derived from subcutaneous adipose tissue (SAT), as a ...

Obesity is a global health concern closely linked to a range of metabolic diseases, such as type 2 diabetes and ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment options remain limited. The HFpEF syndrome is associated with a high ...

Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...

Managing the metabolism of the lipid by-products of ... and biochemical processes that are responsible for membrane lipid homeostasis in bacteria are reviewed. Bacterial survival depends on ...

Impaired lysosomal function (breaking down waste) leads to accumulation of excess lipids in liver cells, worsening NAFLD and contributing to its progression. By analyzing a clinical gene-profiling ...

Further analysis showed that Asah1 deficiency increased harmful lipids accumulation, disrupted lipid metabolism ... by regulating hepatic lipid homeostasis and cellular maintenance processes.

School of Chemistry, University of Leeds, Leeds LS2 9JT, U.K. Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, U.K. School of Chemistry, University of Leeds, Leeds ...

They were aware from previous studies that people born without this gene tend to have issues with their lipid metabolism — the processes by which the body breaks down, transports and utilizes ...