A new study published in the journal Immunity reveals a mechanism that allows triple negative breast cancer (TNBC) to develop resistance to therapy.

A new study published in the journal Immunity reveals a mechanism that allows triple negative breast cancer (TNBC) to develop ...

TFE3 fusion proteins are the oncogenic drivers of translocation renal cell carcinoma but their mechanism of action remains ...

Technological advancements over the past few decades have unraveled the diversity and adaptability of tumors, shedding light ...

Atherosclerosis (AS) is a chronic inflammatory disease characterized by the buildup of lipids and immune cells in arterial ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

Prof. Shan Tizhong's team at Zhejiang University discovered that lard derived from subcutaneous adipose tissue (SAT), as a ...

Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...

Department of Pharmacology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China Guangdong Key Laboratory of Age-Related Cardiac and Cerebral ...

In their review article Chen et al. summarized the main features of metabolic reprogramming in tumors, addressing different aspects including increased glycolytic metabolism, lipid synthesis, ...

Managing the metabolism of the lipid by-products of ... and biochemical processes that are responsible for membrane lipid homeostasis in bacteria are reviewed. Bacterial survival depends on ...

Impaired lysosomal function (breaking down waste) leads to accumulation of excess lipids in liver cells, worsening NAFLD and contributing to its progression. By analyzing a clinical gene-profiling ...