Research led by Lancaster University has discovered that a class of antibiotics—fluoroquinolones—can directly alter the potential bacterial killing ability of one of our immune cells called the ...

Metastasis occurs when cancer cells break away from the original tumor and travel through the bloodstream to form new tumors in other parts of the body. It is the leading cause of cancer-related death ...

1 Escuela de Medicina y Ciencias de la Salud Tec Salud, Tecnologico de Monterrey, Monterrey, Mexico 2 Institute for Obesity Research, Tecnologico de Monterrey, Monterrey, Mexico The intricate ...

Angus Chen covers all issues broadly related to cancer including drugs, policy, science, and equity. He joined STAT in 2021 after covering health and science at NPR and NPR affiliate stations. His ...

Macrophages rely on lysosomes to balance microbial killing with self-protection, generating reactive oxygen and nitrogen species during phagocytosis. Using platinum nanoelectrodes, researchers at ...

Scientists at Trinity College Dublin have discovered that electrically stimulating macrophages can “reprogram” them in such a way to reduce inflammation and encourage faster, more effective healing in ...

Recently these monocyte-derived alveolar macrophages, or Mo-AMs, were identified as key drivers of lung fibrosis disease progression. However, the mechanisms of their pro-fibrotic behavior and ...

The FDA has approved the interferon gamma-blocking antibody emapalumab-lzsg (Gamifant) for the treatment of macrophage activation syndrome (MAS) in known or suspected Still disease. This is the first ...

Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium urate crystals, or MSUc; CPPD disease, another inflammatory joint disease ...

Brain macrophages serve diversified niches in the brain to maintain the organ’s homeostasis, and can play pathogenic roles in age-related brain disease. Hoping to one day replace dysfunctional ...

This study provides insights into the mechanisms by which macrophages mark target cells for programmed cell removal (PrCR). We demonstrate that activated macrophages secrete a C-terminally cleaved ...