When mothers eat a diet high in fat and sugars, their unborn babies can develop liver stress that continues into early life.

When mothers eat a diet high in fat and sugars, their unborn babies can develop liver stress that continues into early life.

Synthesized in the liver, bile acids play diverse roles in digestion and metabolism. However, when their processes are disrupted, disease can occur. Scientists seek advanced technologies to better ...

Effective therapy for NASH is still lacking. In this study, we investigated the effects of Ursodeoxycholic acid (UDCA) in the treatment of NASH. Methods: Western and Chinese databases were ...

When mothers eat a diet high in fat and sugars, their unborn babies can develop liver stress that continues into early life.

How did you discover MCBAs? Bile acids were first described chemically in 1849, and Heinrich Wieland was awarded a Nobel Prize in 1927 for comprehensively describing their chemistry. This ...

Novartis is developing Farnesoid X receptor (FXR) agonists for the treatment of chronic liver diseases, including NASH. The most advanced investigational compound is a potent, non-bile acid FXR ...

Study findings indicate therapeutic potential of microbiome-based intervention to restore bile acid balance and promote gut healing in ulcerative colitis.