is a nuclear receptor expressed in tissues with high oxidative activity that plays a central role in metabolism. In this work, we investigated the effect of hepatocyte PPARα on non-alcoholic fatty ...

Objective To describe the prevalence and variations of non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH) among children and adolescents (CADs) and young adults (YADs).

It also increases risk for liver cancer. Nature journal explains meeting of a healthy liver, NAFLD, NASH and Cirrhosis. NAFLD often has no symptoms. When it does, they may include fatigue ...

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No medication is available to reverse the excessive fat storage in the liver once NASH developed. Therefore, it is urgently needed to unravel the mechanisms of NAFLD in order to accelerate the ...

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(4) Liraglutide is a GLP-1 receptor agonist used clinically to treat type 2 diabetes, which functions by ameliorating the progression of NAFLD in patients with T2DM ... (1) PPARs are members of the ...

The regulation of macrophage polarization in liver is closely related to the progression of NASH. The orphan nuclear receptor retinoic-acid-related ... and Sirius red. NAFLD activity score (NAS) was ...

Activation of a protein called LRH-1 (short for liver receptor homolog-1) that is produced in the ... including type II diabetes and fatty liver disease. However, researchers have been puzzled by the ...