Molecular docking simulations in previous research suggest that acarbose is hydrolyzed by orienting the nucleophile D336 ...
Researchers at the Biocatalysis group led by Dr Francesco Mutti at the Van ‘t Hoff Institute for Molecular Sciences (University of Amsterdam) have developed a novel use of alcohol dehydrogenase (ADH) ...
Oxetanes and other four-sided molecular rings have become increasingly common in drug design thanks to their small size and ability to add three-dimensionality to molecules. There are lots of oxetane ...
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Because of the increasing interests in carbon monoxide (CO) as an endogenous signaling ...
The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.orglett.5c03577. Deposition Number 2445428 contains the supplementary ...