Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

In their 23 cases of NASH cirrhosis, 20 were definite and 3 were probable; ballooning, not a required feature, was noted in 91% of cases and residual perisinusoidal fibrosis was found in 78%.

Novel pathway has potential to slow progression of pulmonary fibrosis Date: March 25, 2025 Source: Elsevier Summary: Researchers have found a potential new way to slow the progression of lung ...

Biomedical researchers have decoded how mechanical forces drive cell behavior in fibrosis. The cells in human bodies are subject to both chemical and mechanical forces. But up until recently ...

Cystic fibrosis (CF) treatment typically involves procedures and medications that help clear the airways. Other treatments may include antibiotics, pancreatic enzymes, a high-calorie diet, and ...

They aid in repairing damaged tissues and influencing the progression of fibrosis. However, despite extensive research on how tissue Tregs interact with immune and non-immune cells during tissue ...

1 Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Department of Basic Medicine, Gannan Medical University, Ganzhou, China 2 Department ...

Background Intestinal fibrosis resulting in stricture formation and obstruction in Crohn’s disease (CD) and increased wall stiffness leading to symptoms in ulcerative colitis (UC) is among the largest ...

EaStCHEM School of Chemistry, University of Edinburgh, David Brewster Road, Edinburgh, Scotland EH9 3FJ, U.K.