LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a role in innate immunity, inflammation regulation and anticancer responses.

Platinum nanoelectrodes measure reactive oxygen and nitrogen species emitted at a macrophage phagocytic cup, revealing how lysosomal pH modulates ROS/RNS flux during frustrated phagocytosis of a glass ...

Background Current treatments with tyrosine kinase inhibitors and immune checkpoint inhibitors have limited efficacy for hepatocellular carcinoma (HCC) due to drug resistance. Emerging therapies such ...

Every day, billions of damaged or unnecessary cells die and are swept away by the immune system’s cleanup crew—phagocytes. But when that clearance falters, dangerous cells can linger, fueling cancer ...

Greg Daugherty has worked 25+ years as an editor and writer for major publications and websites. He is also the author of two books. Katie Miller is a consumer financial services expert. She worked ...

A vivid new image is taking shape in the world of cell biology: Imagine bacteria adhering to the surface of a cell, perhaps at the site of an injury or wound. In response, a white blood cell arrives ...

1 Department of Neurosurgery, Nanjing Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China 2 Department of Neurosurgery, Jiangsu Province Hospital of Chinese ...

Far from a static barrier, the brain’s extensive interface with the blood is increasingly being appreciated as an active border, one that serves not only to keep some proteins out, but to let others ...

COVID-19 vaccination has been the subject of immense scrutiny and misinformation since the vaccines were first administered in the U.S. nearly four years ago. In the first year alone, it is estimated ...

A bizarre bacteria has been discovered with an ability previously thought impossible for its kind. This strange discovery could shine a light on how some of our earliest single-celled ancestors formed ...

A sweeping new definition of long COVID could help affected people get recognition of their condition and improve diagnosis and treatment. The U.S. National Academies of Sciences, Engineering and ...