Scientists uncover how TBK1 and IKKε prevent premature cell death and inflammation
New research from the Kennedy Institute has revealed how two important proteins, TBK1 and IKKε, play a crucial role in ...
EMBO Press4d
A bacterial network of T3SS effectors counteracts host pro-inflammatory responses and cell death to promote infection
Host cells activate cell death pathways in response to bacterial manipulation of innate immune signalling, but the molecular ...
EMBO Press18h
HDAC6 deacetylates ENKD1 to regulate mitotic spindle behavior and corneal epithelial homeostasis
HDAC6 is upregulated in corneal diseases and causes ENKD1 deacetylation at lysine 98. Deacetylation of ENKD1 blocks its ...
The Harvard Crimson5d
HMS Researchers Discover Key Protein in Activating Autoimmune Responses
Harvard Medical School scientists have identified a key protein in the human immune system that drives inflammatory and autoimmune conditions when it turns against the body. The protein, Granzyme ...
pharmaphorum2d
NodThera raises $55m in Series B round to trial inflammatory disease drugs
Proceeds from the financing will be used to advance NT-0167 through clinical studies, further progress the development of additional compounds — including brain-penetrant NLRP3 inflammasome ...
Knowridge3d
Scientists find a “off switch” could help fight aging and chronic diseases
Chronic inflammation is a long-lasting, harmful response by the body’s immune system. It can quietly damage organs and tissues over time and is linked to serious illnesses like Alzheimer’s ...
newsbytesapp.com2d
Astronauts are falling sick on ISS because it's too clean
Astronauts aboard the International Space Station (ISS) have been suffering from a variety of health issues, from persistent rashes and strange allergies to infections from fungi, shingles, and ...