Background/aim: 5-Hydroxytryptamine (5-HT) released from enterochromaffin cells influences intestinal homeostasis by altering gut physiology and is implicated in the pathophysiology of various gut ...

New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain ...

Explore how the ratio of pd-1+ treg to ctl and the presence of tertiary lymphoid structures can influence treatment outcomes ...

Researchers have long focused on the STING (Stimulator of Interferon Genes) pathway as a way to harness the immune system's ...

Recent advancements in dermatology have highlighted the crucial role of dermal T cell immunity in regulating hair follicle regeneration and addressing ...

Researchers from MIT and Scripps have unveiled a promising new HIV vaccine approach that generates a powerful immune response with just one dose. By combining two immune-boosting adjuvants alum ...

We hypothesized in this clinical trial design that patient-specific variations of the innate immune system might affect the heterogeneity of response observed with TVEC as previous reports in both OV ...

The experiment was a striking attempt to investigate weight control. For six weeks, a group of mice gorged on lard-enriched mouse chow, then scientists infected the mice with worms. The worms wriggled ...

Despite the considerable promise of ICB, only about half of treated patients experience response, with many others experiencing primary or acquired resistance to ICB (2, 3). Additionally, toxicity ...

Background Immune responses on SARS-CoV-2 vaccination in patients receiving anti-CD20 therapies are impaired but vary considerably. We conducted a systematic review and meta-analysis of the literature ...