For decades microtubule-targeting agents (MTAs) have been a cornerstone of cancer treatment regimens and continue to be heavily employed as backbone chemotherapy in combination with new targeted ...

Results from Phase 2a Trial demonstrate a good safety and tolerability profile of VXM01 and Avelumab Combination Therapy in ...

These immune killer cells then actively destroy cells in the tumor vasculature, leading to an increased infiltration of various immune cells into the tumor. In several tumor types, including brain ...

Early results show that the combination of VXM01 plus avelumab demonstrated tolerable safety in recurrent glioblastoma.

The VXM01-avelumab combination therapy was generally well-tolerated, with the majority of safety events being mild to moderate in severity. These safety and tolerability data are in-line with ...

Immunology is the branch of biomedical sciences concerned with all aspects of the immune system in all multicellular organisms. Macrophages can recycle nutrients and metabolites from bacteria that ...

Macrophage infiltration in various solid tumors is associated with ... by directly enhancing malignant biological behaviors or by engaging in crosstalk with immune cells present in the TME to promote ...