An increase in high-fat, high-fructose foods in people's diets has contributed to a dramatic increase in type 2 diabetes. This, in turn, has led to an increase in peripheral neuropathy—nerve damage, ...

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.

When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

Macrophages are the specialized phagocytic cells that respond to toxic particle depositions to exert inflammatory and clearance responses. These long-lived immune cells engulf foreign substances like ...

In regenerative medicine, macrophages and stem cells play pivotal roles in repairing central nervous system (CNS) injuries. These cells are instrumental due ...

The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer. Chief among this force is the macrophage, a white blood cell that surveils tissues ...

Trojan horse” approach may enable ‘antigen-independent’ therapy with potential to treat cancers not traditionally amenable to immunotherapy.

Could our immune system’s response to bacteria hold the key to better treatments for immune-related diseases? In a recent study published in Nature, a team of researchers explored how macrophages—our ...

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an ...